
Prof. Paul Lee
MBBCh · MSc (Sports Med) · MFSEM (UK) · MRCS · FEBOT (Eu) · PhD (Medical Engineering) · FRCS (Tr & Orth)
London & Lincolnshire, United Kingdom
Consultant regenerative orthopaedic surgeon, internationally recognised in cartilage repair and joint preservation, and founder of MSK Doctors Research.
Biography
An internationally recognised specialist in cartilage repair and joint preservation, Professor Paul Lee is a consultant regenerative orthopaedic surgeon and the founder of MSK Doctors Research. He established the London Cartilage Clinic on Harley Street, an ICRS Teaching Centre of Excellence, and MSK Doctors in Lincolnshire, where clinical care, imaging, artificial intelligence and regenerative therapies are brought together in one pathway.
His surgical work spans a ladder of cartilage-regeneration techniques, progressing from traditional ACI and MACI to the single-stage STACi procedure and the bedside Nano-ACi application. He performed the first UK Arthrosamid treatments for knee osteoarthritis and has since treated more than 1,000 cases.
He holds a PhD in Medical Engineering and is Honorary Professor of Sports Medicine at the University of Lincoln. He is Editor-in-Chief of Musculoskeletal Regeneration Medicine (Springer Nature), the author of Regeneration by Design and Practical Regeneration, and has more than 100 peer-reviewed publications. He is also the Founding President of I AM Regen, the International Association of Musculoskeletal Regeneration.
Selected publications

Musculoskeletal Regeneration Medicine
Regenerative Medicine Across AI, Engineering, and Clinical Orthopaedics. The international Springer Nature reference textbook, bridging regenerative orthopaedic surgery with AI-driven diagnostics, next-generation orthobiologics and engineering-led clinical thinking.
View on Springer Nature- 01Regeneration by Design: The Science of Superhuman Ageing (Rethink Press, 2024) — Amazon #1 international bestseller
- 02Practical Regeneration — the applied companion to Regeneration by Design
- 03Briefs in Tissue Repair and Reconstruction (Springer Nature) — Section Editor, Orthopaedics
- 04More than 100 peer-reviewed publications
Presentations with MSK Doctors Research
- 2025The Human AlgorithmSorbonne Université, Campus des Cordeliers, Paris · Lecture
- 2025MAI MotionUnited European Academy Conference, Casablanca · International conference presentation
- 2025Biomechanical Comparison of Sit-to-Stand and Squat Using the CRAFT Framework and MAI Motion AnalysisBritish Orthopaedic Association Annual Congress 2025, ACC Liverpool · Scientific presentation
- 2025Does Markerless Motion Analysis Predict Movement Quality after Intra-articular Orthobiologic Injections?2nd European Symposium on Interprofessional Collaboration on Osteoarthritis Management · Scientific presentation
- 2025onMRI2nd European Symposium on Interprofessional Collaboration on Osteoarthritis Management · Scientific presentation
- 2026Evaluating the Effect of Electrical Muscle Stimulation (EMS) on Post-Operative Musculoskeletal Function and RecoveryBOA Annual Congress 2026, Olympia London · Abstract ID 922 · 8th ICRS Summit 2026, Porto · A0 e-poster
- 2026ChondroFiller as a Single-Stage Treatment for Knee Cartilage Defects: Early Clinical Outcomes8th ICRS Summit 2026, Porto · A0 e-poster
- 2026Clinical Outcomes Following Ultrasound-Guided ChondroFiller Injection for Ankle Cartilage Defects8th ICRS Summit 2026, Porto · A0 e-poster
- 2026Relationship Between Radiographic Knee Osteoarthritis Severity and Hip Movement Quality in Patients Without Hip OsteoarthritisBOA Annual Congress 2026, Olympia London · 8th ICRS Summit 2026, Porto · Scientific e-poster
- 2026Movement Quality After Intra-articular InjectionsTurkic-Speaking Countries Orthopaedics & Traumatology International Congress (TOTBİD & Azerbaijan Orthopaedic Society), Baku Marriott Hotel Boulevard, September 2026 · Abstract SB-040 · Oral presentation
- 2026Surgery Through a Needle18th Annual Reconstruction Conference (ARC), hosted by United Orthopedic Corporation, Kuala Lumpur, Malaysia · Invited lecture
- 2025Invited Lecture17th Annual Reconstruction Conference (ARC), hosted by United Orthopedic Corporation, Hanoi, Vietnam · Invited lecture
- 2024Invited Lecture16th Annual Reconstruction Conference (ARC), hosted by United Orthopedic Corporation, Bangkok, Thailand · Invited lecture
- 2023Invited Lecture15th Annual Reconstruction Conference (ARC), hosted by United Orthopedic Corporation, Taiwan · Invited lecture
- 2023Invited LectureUnited European Academy Conference, Barcelona · Invited lecture